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Thorn for srs Crucible, Pocket Infinity for lulzy Crucible (seriously, this thing makes people do hilarious things), and I actually don't have a favorite for PvE. I swap weapons very regularly in PvE. When I'm not needing heavy firepower, I'm using Thorn. When I do need it, I'm using Gjallarhorn. When I need something for those bloody Minotaurs, I have a fusion rifle. When there's shielded Shanks, -blam!- them, I have a sniper and very well content hanging out back until they are dead. Seriously. -blam!- shielded Shanks in Nightfalls.