Slow reload speed, fast ammo depletion, and small ammo cap make shotties a non-viable alternative in PVE under many, but not all, situations. However, I just got Invective and am leveling it up. Once I am able to use the fitted stock for better stability, I think this will be a fun gun to use on a more regular basis. The problem with ammo cap is still there though.
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Try the "Secret Handshake", it has nice rate of fire. Only thing bad about it is the lack of ammo.