From what we have seen so far, killed enemies will disintegrate without any blood effects. This really bothers because it looks so unreal and stupid. I don't want the game anywhere near as gory as Gears of War, but I want some realistic blood effects and ragdoll to balance out all the space magic.
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The fallen don't disintegrate. I'm pretty sure it's only when you use elemental weapons or focus abilities that enemies do. I agree with you about the lack of blood spatter though. It just feels like you're using an air rifle or something with out it.