Pictured above are the three different pictures from destiny gameplay/trailers that all have different abilities. I think that this proves that there will be a choice in what abilities you use, seeing as these pictures are all Warlock gameplay.
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The 4 known warlock Abilities are:[/u]
Radiance: AOE magic air-ground pound
Solar flare: 'Nade
Nova bomb: Big 'Nade
Glide: Magic Jetpack
And then we have the one represented by symbols in the pictures above that haven't been shown
[u]
The 2 known (I think) Titan abilities are:[/u]
Some sort of bubble shield thing
Fist of havok: AOE electric ground pound
[u]And finally the known Hunter abilities are:[/u]
Golden gun: Supercharges your gun in flames
something that supercharges your knife, but in a white/blue energy
a sort of forward dash wherein the Hunter is launched forwards very quickly.
Lots of red grenade thingy explosives that home in on enemies.
And there also may be double jumping but I'm not sure about that one.
Now seeing as there are only so many buttons on a controller I think that this proves that Abilities will be highly customizable. Of course Destiny is still a work in progress so...
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What do you mean by powers being customisable?