For me, it is when they make guys look like freaking chicks and I can never tell which one they are. This goes for Haku from Naruto and some guy from Sengoku Basara whose name I forgot.
EDIT: Also, chicks with extremely oversized breasts.
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Sometimes they'll take too long to get to the point. giving a character extra screen time or a special about them means they're getting killed off soon. bad english dubs pointless filler spending half the episode recapping what's already happened The "recap episode" where they just show clips of shit that happened already in order to fill space. Having a cliffhanger only to have an anti-climactic resolution the next episode. hero losing a single fight then turning emo for 5 episodes