For me, it is when they make guys look like freaking chicks and I can never tell which one they are. This goes for Haku from Naruto and some guy from Sengoku Basara whose name I forgot.
EDIT: Also, chicks with extremely oversized breasts.
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-the fanbase (cosplaying will never be cool) -the haters (saying you hate anime is like saying you hate music) -little girls (referring to yourself in the 3rd person isn't cute, shut up) -1 dimensional characters (oh, you're unpopular? time to sit in the back if the class and stare out the window all f*cking day) -tsunderes (pulling frying pans out of nowhere will never be even remotely funny) -slice of life (ultimate drawing abilities? time make a show about high school kids) and the list goes on to knit-picking, but among all the stupidity there are gems to be found.