For me it was in Fallout New Vegas. I started a new play through and I wanted to get over to New Vegas. I managed to reach the Junction 15 railway station by going through Black Mountain. I fast traveled back to Goodsprings to sell somethings and I was hoping a Deathclaw near me was gone. When I fast traveled to the station there were 2 Deathclaws about 20 feet away me. I said, "Oh, Lord Jesus, they're Deathclaws." Then I ran out of the station. I didn't grab no caps or nothin', Jesus. I ran for my life. Soon after that the 2 Deathclaws turned into 3 then the 3 turned into 5. And then the Deathclaws got me. So I ended up getting rap3d faster than a drunk teen at a party.
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Halo 3 - Narrows Worst Spawns EVER! Also on Halo 3 during the vidmaster run you may respawn after dying behind where the bottom was just about to drop out of everything. Nearly any CoD TDM game with stupid randoms who CONSTANTLY flip spawns.