I know a lot of us here aren't fond of either social network, but I've used Facebook frequently for a couple of years now, and now all of my friends are saying twitter is where it's at. I'm not sure if this is a widespread thing going on or just in my area (which is probably the case). I have a twitter, but I cannot for the life of me understand how you could prefer something with less features than Facebook (no chat, no good way to present photos, etc).
I used to dislike Facebook, but it was a great tool for communicating with friends. I think twitter is only for those who want more attention for their statuses.
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I use both. I keep all my internet friends and interests on my twitter and all the people on facebook are friends and family.