Hi! I've also had a lot of time spent on trying to fix this annoying error. I ended up having a faulty RAM stick and replacing it did the trick so far! I've been playing for 2 days (~8-10hrs) without any crashes now. [b]Here is a list of what I tried and I suggest you do to:[/b] [b]1.[/b] [url=https://help.steampowered.com/en/faqs/view/6AD7-820D-8BE5-E51F]Clearing Steam download cache[/url]. [b]2.[/b] [url=https://help.steampowered.com/en/faqs/view/0C48-FCBD-DA71-93EB]Verifying integrity of game files[/url]. [b]3.[/b] Update GPU driver to the latest version. [b]4.[/b] Changing Destiny 2 ingame settings to default. [b]5.[/b] Turning off Windows Game Mode. [b]6.[/b] Resetting Nvidia Control Panel Settings (If you are using Nvidia). [b]7.[/b] [url=https://help.steampowered.com/en/faqs/view/4BD4-4528-6B2E-8327#move]Changing the drive Destiny 2 is located on[/url] if possible. [b]8.[/b] Reinstalling Destiny 2. [b]9.[/b] Reinstalling windows. If none of these fix it for you, try checking your RAM sticks for failures. If you have 2 or more RAM sticks test them each individually and check if you still get an error. If you are still getting the error try getting a new RAM stick (any cheap one that works good enough will do) just to make sure RAM is not the issue. If you have tried all of this I'd personally just give up until you get more things to try, It is not worth replacing any other parts in your pc if you are only having this issue with Destiny 2, it will cost too much imo (unless you find it worth it). Let me know if you have any questions.

Are you using steam?