Instead of having to manually reselect every perk again and again each time we want to swap some perks it would be much better to be able to turn off just the perk you want to swap, then select another, turning 13 times holding the mouse into just two clicks.
I'm pretty sure it can't be hard to implement this without breaking the "select N perks to access this column" system — whole columns could just become disabled without unslotting the perks from them while we're swapping perks in other columns.
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Maybe it works like a weapon with a bunch of trait options. In each column you get a number of sections and each time you exceed it, the topmost selection gets unselected. No resetting or re selecting everything just click on your choices and go