You are insignificant. I am insignificant. We are all insignificant in this unfathomably large universe that has no reason to care about a single species that doesn't help its own kind in need and that still kills each other over skin color, what others want to do with their genitals, and which version of the invisible man in the sky to believe in.
Let go. It will set you free.
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It's not that the universe has no reason, it's more the fact that the universe, as far as we are aware, does not have the ability to care. You know, because it's (probably) not a sentient being?