titans are essential for the way we ran, bring as many as possible, 2 in the middle with a weapons and blessing bubble and melt the ogres, hit them as soon as they appear, stop them from moving, sometimes teleporting. Touch of malices melt them quick and the middle titans take care of the 4th night.Our team was 3 titans, 2 warlocks, revives really help, plus the 3rd titan can pop his bubble if things get hairy, last was a nightstalker hunter to run and create orbs with his super.I imagine it's possible without the defenders, but they really help.