This has probably been done already, but we're doing it again!
Alight everyone, get posting! :D
Here's mine:
Friend: I -blam!-ed your mom last night.
Me: So you're the one who gave her AIDS!
-
Friend: Retard Me: I have a comeback, but I can't use it because my parents told me to be nice to the mentally challenged. [spoiler]+10 points for trying[/spoiler]