So I saw someone get this Relic, and I thought I had a good idea of a place nearby to take it.
For anyone who already knows about this chest, it will negate the necessity to use damage reducing supers, or other 'cheap tricks.'
In other words, this is the correct way to get the chest in the blighted cave in Hall of Souls.
Please leave the Vid a like if it helped, and be sure to let your friends know.
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Looks like a lot more people know about this now.