I've noticed after update 2.0 that every once in a while now, the audio will cut out for a tenth of a second, like it's skipping a beat or getting overwhelmed.
I think it happens at random, but I've noticed it for example while running patrol on Venus, before or after Ghost is speaking. It was always flawless before, all throughout Year One.
I'm on the PlayStation 3, running the Blu-Ray disc copy, with The Dark Below and House of Wolves installed.
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Just did the S.A.B.E.R. strike for the first time, and the audio was clipping out like crazy. Sometimes a couple of times a minute.