Chemistry is a deep and rich subject it's amazing what can be achieved with it. If our appreciation of beauty comes from some intangible spirit then why does changes to brain chemistry and make up affect it? Such as? And is it that they don't make sense to you in your ignorance of the subject or that they actually don't make sense to those that actually understand neuroscience? You are aware aren't you that to prove spirit is required as an explanation you have to provide actual ways it explains things and not just say what you don't know about science?