My tips 1.Take it slow... one of the best things about fallout is planning ahead for example befor you explore bring some supply's with you like food and ammo. Also Enjoy the game don't rush it 2. Explore with different play-styles be for committing... Try small guns, then try big guns, try vats, then try sneaking... Trying multiple approaches to a situation befor you make your mind up 3. Save often.. Believe me this is probably the most important tip, playing the game for hours straight to die in the wasteland n not saving might make you want to quite all together 4 talk to everyone, People are often the main source of quests, so make sure you try and exhaust the dialogs 5. When your done playing get ready to play fallout new vegas!! I hope you enjoy fallout3, fallout 4 is around the corner so getting into 3 now is a smart move