Pretty straightforward question. Personally, I'd love a patrol in an iconic "ancient" city, such as New York, Hollywood, Tokyo, London, etc. I think it would be super cool to explore post-apocalyptic versions of cities that we're already familiar with. Also, a large patrol area filled with tons of tight corners, streets, buildings, and whatnot would be a nice mix-up from all the open areas we have now.
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Chicago would be neat as hell, as would New York. Hell, even Indy and Louisville.