This includes fantasy and sci-fi.
My choice is the Combine.
A multi-universal species from half-life so absolutely immense and powerful that they reverse-engineered earth's technology, upgraded far beyond human ability, brainwashed some humans and had them invade themselves. They did this and stomped all resistance within 7 hours. This was done by a backwater lesser combine city mind you.
-
I have 2 cases here. 1.HellSpawn(Spawn/Al Simmons only, the rest are bitches) 2.Tenno. Nova Prime+Frost Prime+Nyx Prime+Zephyr=[u]Dead[/u].