Not always, if there smart they stack the bubbles close to one another but seperate enough that a nova bomb only hits one of the bubbles and leaves the others standing. Promptly after the titan 're-bubbles since the unlimited amount of orbs spawning. FoH is really the only way to disperse them but you have to dodge the golden gunner. Problem then is that they spawn with full super again and just setup once more.
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Drop the bom in the bubble u get them all