https://www.youtube.com/watch?v=c7rJLQlZTY4
The old guides on this dont work anymore because chests take forever to respawn in an area. Going into another area usually doesnt fix it. If you open 5 or 6 chests within 3 minutes they stop spawning for a 5 to 10 minute period. Using this method you can get around that and get your hadium flakes done very quickly.
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Just do a loop around hull breach when you first land on the dreadnaught. Start on the right side and loop around to the far left and back to the cave under the landing/ spawn area. You'll find 4-5 chests during every loop. 3 spawn caves on the right, one chest usually spawns by the main Cabal area and the last under the spawn area in the cave with the Wormsinger terminal.