I would say the destiny universe as we are a MUCH larger scale, organised, equipped military force. Along with the fact we seem to be working with slightly higher levels of standard tech in the destiny universe. Borderlands has high tech gear, high functioning robotics, implants, energy weapons and accurate teleportation. In destiny we have that and we take it further by having accurate teleportation that doesn't require a "anchor," higher quality robotics simulating at the hardware and AI level true human intelligence. We have limited dimensional and time travel. We have wider availability to the effect the sirens use through our warlocks. We however do not have a deep level of understanding of our tech, since we are just now REALLY learning about the tech we have. So borderlands has that going for them. but I think the lack of a true proper and large scale military is the largest reason.